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A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease. Results: Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125.

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O exame de CA-125 serve, principalmente, para monitorar o tratamento do câncer de ovário. Também pode ser usado para detectar se o câncer voltou após o tratamento estar completo. O teste por vezes é utilizado para testar e monitorar as mulheres com alto risco de câncer de ovário, mas que ainda não têm a doença.

Tumor marker CA125 Women Health Info Blog


Discussão. Neste artigo, confirmamos que em uma amostra de mulheres com sintomas sugestivos de endometriose submetidas a tratamento cirúrgico laparoscópico, a presença de níveis séricos elevados de Ca-125 elevada no pré-operatório está fortemente relacionada à presença de formas mais severas da doença, de endometrioma ovariano e de EPI.

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A endometriose é uma doença que afeta muitas mulheres em todo o mundo, causando dor, infertilidade e outros sintomas desconfortáveis. Uma das formas de diagnosticar a endometriose é através do exame de CA-125, que pode indicar a presença da doença no organismo. Neste artigo, vamos falar sobre o que é o CA-125, como ele está […]

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CA-125, a cell-surface antigen, was measured by a radioimmunoassay in the serum of 414 women to determine its potential usefulness in the diagnosis and management of endometriosis. In women with minimal, mild, moderate, and severe endometriosis, the mean levels (± standard deviation) were 13.6 ± 6.8,22.8 ± 15.5,27 ± 17, and.

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Endometriosis is a benign gynecologic disease defined as the presence of functional endometrial glands and stroma outside the uterine cavity, causing dysmenorrhea, dyspareunia, menstrual irregularities, and infertility. Serum CA-125 measurement is now a consolidated method for diagnosing this condit.

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Objective. To demonstrate the relationship between presurgical levels of Ca-125 and Ca 19.9 and grade of endometriosis. Subjects and methods. We performed a retrospective study of a random sample of 85 patients who underwent surgery for endometriosis in the Hospital General Universitario de Alicante (Spain) between February, 1996 and January, 2003.

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Serum CA-125 values were lower in midcycle than in menstrual phase, in both groups. Median CA-125 in the midcycle phase were 39.5 IU/mL (range 11.9-200.0 IU/mL) in DIE group and 16.4 IU/mL (range 5.4-30.8 IU/mL) in controls. Median difference between DIE group and controls in the menstrual phase was 23.1 ( p < .001).

(PDF) Immunoreactive determinants of CA 125 in women with endometriosis


Knowledge of the factors influencing serum concentrations of CA 125 have led the validity of a single cut-off value to be questioned. The aims of the present study were to evaluate CA 125 levels according to age, menopause, body mass index (BMI), smoking, parity, variability during the menstrual cycle, biological variation, index of individuality (II), and critical difference (CD).

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For women with symptoms suggestive of endometriosis, serum CA 125 is a relatively specific (93%) and noninvasive test. It can be used to make a presumptive diagnosis in cases for which a medical.

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The serum CA-125 level is elevated in most women with endometriosis. Although tests are readily available to measure the marker, simple modifications of the present assays are required to improve and standardize the quality of the measurements. The serum test has low sensitivity and would not be appropriate for general screening purposes, but in clinical situations that have a relatively high.

(PDF) Endometriosis Use of a new CA 125 assay in the diagnosis of endometriosis


A endometriose é uma condição médica comum caracterizada pela presença de tecido endometrial fora do útero, geralmente na cavidade abdominal, ovários e trompas de Falópio. Embora os sintomas possam variar de leves a graves, a endometriose pode causar dor pélvica crônica, dispareunia (dor durante a relação sexual), irregularidades menstruais e infertilidade. A endometriose pode ser

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CA-125 and Endometriosis. CA-125 is a protein that is a tumor marker or biomarker, which is a substance that is found in greater concentration in tumor cells than in other cells of the body. In particular, CA-125 is present in greater concentration in ovarian cancer cells than in other cells. CA-125 levels are high in about 1% of healthy women.

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CA 125≥30u/ml is highly predictive of endometriosis in women with symptoms of pain and/or subfertility. CA 125 should be considered as a rule-in test for expediting the diagnosis and management of endometriosis, CA 125 <30u/ml is, however, unable to rule out endometriosis.

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Se você já recebeu o diagnóstico de endometriose, provavelmente já ouviu falar do CA 125. Esse exame é frequentemente solicitado para ajudar no diagnóstico e monitoramento da doença, mas nem sempre é fácil entender os resultados. Neste artigo, vamos explicar o que é o CA 125, como ele é usado para diagnosticar e monitorar a […]

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CA-125 is a cellular antigen detected in many patients with ovarian cancer, but it has also been detected in patients with endometriosis. Preoperative CA-125 levels were drawn from 113 patients before they underwent laparoscopy. Patients were categorized into diagnostic groups on the basis of pathologic findings.

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